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We examine far from equilibrium systems and we focus in particular on the production of global entropy associated to the irreversible character of the processes. A traditional balance equation for the metabolism will then be extended to the new notion as specified by these principles. To this purpose, we introduce two principles, in addition to the thermodynamic ones, which are (mathematically) compatible with traditional principles but which have no meaning with regard to inert matter. This paper proposes a systemic perspective for some aspects of both phylogenesis and ontogenesis by expressing biological organization in terms of "anti-entropy", a notion to be defined below and which conceptually differs from the common use of "negative entropy".
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